Chromatin bridges
Healthy cell division: Metaphase: Chromosomes line up at the cell’s center. Anaphase: Chromosomes separate cleanly toward opposite poles. Telophase: Two nuclei form with fully separated DNA. Result: two daughter cells with the correct DNA, stable genome. Unhealthy division with chromatin bridges: Metaphase: Chromosomes may be tangled or improperly aligned. Anaphase: Some chromosomes fail to separate , and their DNA gets stretched between the two poles. Telophase: Thread-like DNA bridges remain between nuclei. Result: DNA may break or mis-segregate, producing cells with abnormal DNA and genomic instability .